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Further studies are needed to evaluate sensitization after repeated doses and to study the effect of additional CFP-10 on the sensitivity of a TB-specific skin test.
Thus, although these six sites were not considered positive findings in this study, future epigenetic studies that utilize SPTs to evaluate sensitization, and evaluate sensitization in young adults close to age 18, may consider attempting to replicate these sites.
The aim was to evaluate sensitization and CPM in computer users with and without chronic musculoskeletal pain.
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Available studies on this topic have evaluated sensitization in a limited number of children and/or are based on high-risk populations [ 6, 13].
Additionally, lymphotoxin alpha could also be useful for evaluating sensitization to metals [ 10] in allergic diseases, for testing vaccine efficacy [ 11], and for assessing the effect of new immunostimulatory drugs [ 12].
Some patients underwent rechallenge to evaluate contact sensitization and none displayed conclusive contact sensitization.
Other tests used to evaluate respiratory sensitization include eosinophil counts in blood or sputum and skin prick testing (SPT).
In addition, the development of bioreactors enabled scientists to avoid the use of ascites as a source for monoclonal antibodies and are now used to simulate various organs, including the human lymph node, to evaluate the sensitization potential of chemicals or pharmaceutical substances (Giese et al. 2006).
This study was designed to evaluate the sensitization potential of a CPE extracted during active fish kill conditions (90 100% mortality in 48 hr) associated with a Pfiesteria isolate in a standard fish bioassay, and to determine whether the inflammation and dermatitis reported in early human exposure studies were allergic or irritant in nature.
However, a recent cohort study that evaluated incident sensitization in dental hygiene students suggests strongly that, with sufficient exposure, employment in health care can lead to an increased risk of IgE sensitization to natural rubber latex.
This discrepancy was even more evident when we evaluated the sensitization based on the number of years the migrants had spent in Singapore (Fig. 3D, Fig. S2B).
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