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After introducing our conceptual framework, we will use field data to systematically evaluate linkages and feedbacks between ecology (rainfall and vegetation), resource generation (pastoral productivity), and household wealth among Mukugodo pastoralists.
Euclidean distance is commonly used to evaluate linkages in the expression of different genes.
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The multilocus 1.2 software [61] was used to calculate the standardized index of association (IA) and evaluate linkage disequilibrium among the loci.
TASSEL 1.9.6 was used to evaluate linkage disequilibrium (LD), extract polymorphic sites, calculate narrow sense heritability, and perform General and Mixed Linear Models (GLM, MLM) with incorporation of trait data, population structure (Q) and kinship matrix (K) [59].
For the microsatellite data, GENEPOP v4.0 [22] was used to evaluate linkage disequilibrium (LD) between all pairs of loci for each population (1000 dememorization iterations, 1000 batches, 10000 iterations per batch) and Hardy-Weinberg equilibrium (HWE).
We used χ to evaluate Hardy-Weinberg equilibrium and Haploview to evaluate linkage disequilibrium.
To evaluate linkage quality, three standard metrics were used: precision, recall and F-measure [ 21].
D′ was calculated to evaluate linkage disequilibrium for all pairwise SNP combinations.
In contrast to methods that evaluate linkage conditional on association, Li et al. [2005] jointly modelled linkage and association in a region.
However, there is still an urgent need to evaluate linkage models that connect clients to HIV care from testing locations outside of HIV medical care settings.
To evaluate linkage disequilibrium (LD), exhaustive intrachromosomal pairwise calculations of the disequilibrium coefficient, r, were computed between SNPs within each chromosome, using the program PLINK v1.07 (Purcell et al. 2007).
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