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5-Fluorouracil is a good candidate to evaluate in combination with docetaxel, since both agents are effective against metastatic breast cancer, but have different mechanisms of action and tolerability profiles.
It is an interesting drug to evaluate in combination with TNF because incubation of tumour cells with actinomycin D has been shown to increase their sensitivity to the effects of TNF (Alexander et al, 1987).
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Many clinicians and decision makers want to know the combined effects of treatments that have not been evaluated in combination.
Rapamycin analogs are sufficiently tolerable to be evaluated in combination with other agents, and are presently the only agents one can feasibly combine with emerging BRAF or MEK inhibitors.
Over the years, the MCAT has gone through four major revisions and has only strengthened its ability to predict success in medical school, particularly when evaluated in combination with grades.
However, these three tests have not been evaluated in combination.
The performance of this system was evaluated in combination with a commercial fiber optic oxygen sensor.
In this study, gamma camera-based freehandSPECT was evaluated in combination with the hybrid tracer ICG-99mTc-nanocolloid.
The amount of ammonia produced by these gene-deleted strains was evaluated in combination with the overexpression of kivd in M9-YE medium.
In this study, the PARP inhibitor ABT-888 was evaluated in combination with and compared to current standard-of-care in a genetically engineered mouse GBM model.
These amperometric detectors have been evaluated in combination to poly methylmethacrylate) (PMMA) and Topas (thermoplastic olefin polymer of amorphous structure) CE-microchips.
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