Sentence examples for evaluate downstream effects from inspiring English sources

To evaluate downstream effects of forced over-expression of each protein over the others, we transfected HeLa cells, which show the lowest transcription levels of the genes of interest, with ALK, PHOX2A and PHOX2B cDNAs expressing vectors.

Since PUMA up-regulation and Bax translocation have been shown to release cytochrome C from the mitochondria and activate caspase-9 through mitochondrial pathway [ 12, 18], we performed caspase-9 activity assay to evaluate downstream effects of PUMA and Bax in E2F-1-induced apoptosis.

Incorporated into the method is the newly defined "heat duty flow-on" factor, θ, which evaluates downstream effects on utility use and cost that are caused by changing the area of one exchanger.

To assess downstream effects promoted by AE expression and to evaluate the time needed to induce a phenotype, haematopoietic parameters were monitored.

We suggested further research applied to different clinical settings to evaluate the downstream effects (subsequent tests, procedures, patient outcome and condition-related cost of care) of two testing strategies – one that utilizes US and another for CXR.

In this study, we evaluated the downstream effects of extended processing times on the reliability of aneuploidy detection by massively parallel sequencing (MPS).

Nevertheless, these data underscore the need for further prospective research that evaluates the downstream effects of interventions, which are aimed at preserving muscle mass, on muscle strength and physical function.

We next evaluated the downstream effect of the environment produced by the early recruitment of IL-10+/CD206+ Mϕ by CSCL, analyzing CSCL explants at 3 and 7 days.

'Downstream effects' were evaluated by measuring NOS activity, nitric oxide (NO) production, and interleukin-8 concentrations.

We searched for evidence of distinct downstream effects by evaluating the effect of distinct pairs of Cdx MOs on gene expression (Fig.  2d g).

Therefore, its bioavailability is usually evaluated in humans by measuring the downstream effects, namely the vasodilation induced by the local stimulation of NO production by specific external mechanical and pharmacological stimuli, i.e., through vascular reactivity tests (4).