Disruption of the NoDS/intergenic RNA interaction enables proteins to evade nucleolar sequestration and retain their dynamic profiles.
SOX2 is intricately involved in many cancer-associated processes such as cell proliferation, evading cellular apoptosis and metastasis via interactions with EGFR signaling and several other oncogenic pathways and processes.
For therapeutic purposes it is also important to understand how OS cells evade Fas-induced cell death triggered by the interaction of Fas with FasL.
These data suggest that HIV-1 may evade T-cell dependent IgA and IgG responses through interaction between nef and B-cells [21].
Outer membrane proteins may contribute to the modulation of bacterial cell surface properties during interaction with the host, thus playing a role in evading host immune response [ 18].
In Cyanobacteria, therefore, constriction of carotenoid diversification due to interaction with the photosynthetic reaction centre may be evaded by partitioning of different carotenoid structures into different functional roles.
Alternatively, muscadine isolates may have alleles that evade recognition by host defences in a gene-for-gene interaction.
Although these organisms are extremely varied in their biological structure and interactions with the host, they share similar methods of evading the host immune system.
It is possible that the interaction is too weak or transient, and that it therefore evades detection in our system, even though we can detect interactions between the two proteins when both are overexpressed.
Given that host defenses against parasites are predominantly mediated by proteases, it's widely hypothesized in parasite and host interaction studies that parasites including ticks could utilize protease inhibitors to evade host defenses [ 131, 132].
HCV has developed a range of mechanisms for evading the cell's defenses, modulating the apoptosis of infected cells as, for instance, the interaction with PKR (a dsRNA-dependent protein kinase).
