We thus propose that certain features of metal complexes can be harnessed in the design of new reagents targeting polar and repetitive IDRs that have largely evaded intervention by traditional organic small-molecule modulators.
Eventually, however, the tumours evade treatment control.
(That is why people take cocktails of H.I.V. medications; the combinations help slow the rate at which the virus learns to evade those interventions).
In both cases, consensus emerged that somatic (within-body) cellular selection and evolution is the fundamental process by which neoplasms arise, acquire malignancy, and evade therapeutic interventions (Frank and Nowak 2004; Crespi and Summers 2005; Maley and Reid 2005; Merlo et al. 2006).
Genital cutting is a deeply entrenched cultural practice that also evaded a legislative intervention; Tostan raised awareness about the health and human rights implications of cutting in grassroots discussion groups, slowly building consensus against the practice that led to public pledges.
In July BNP Paribas, France's biggest bank, was fined nearly $9bn£5.4bnby) by US regulators for helping some customers evade US sanctions, despite an intervention from President François Hollande, who lobbied the White House against "unfair and disproportionate" penalties.
A CRISPR/Cas9 treatment would evade medical malpractice law due to the early stage of the intervention and the fact that it is not a treatment for the mother.
These may represent high-risk locations, where reassortment could facilitate evolutionary innovation and lead to the emergence of novel lineages with the capacity to evade host immunity, expand host ranges, or overcome treatment interventions.
Giovanni evades every human challenge, and it takes supernatural intervention to punish him as he deserves.
Abnormalities incapacitating these finely tuned processes provide a strong advantage for cancer clones to succeed in evading both the physiological control systems and therapeutic intervention.
They evaded Serb responsibility for the atrocities and vastly overestimated the difficulties of intervention.
