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A large meta-analysis (including 11,345 patients from 68 studies) performed recently indicates that patients with autosomal dominant polycystic kidney disease (PKD), IgA nephropathy, membranous nephropathy, or chronic renal disease of unspecified etiology progress more quickly to ESRD [4].
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Irrespective of the nature of the primary disease and the originating renal compartment, renal fibrosis is considered to be the common final pathway by which kidney diseases with variable etiology progresses to end-stage renal failure.
Rodent models are an indispensable tool for studying etiology and progress of depression.
Migraine is a chronic, progressive neurological disorder with unknown etiology, and progresses with episodic headache attacks [ 3].
49 Other observational studies showed that insulin resistance is present in mild kidney disease, irrespective of its etiology, and progresses as kidney function diminishes.
Given persisting fibrogenesis without removal of exposure to the specific etiology, liver fibrosis progresses.
But does each step toward neoplastic transformation recapitulate the morphology, pathology, and etiology of the progressing disease?
Identification of common genetic pathways underlying these symptoms and complications can provide clues to better understand the etiology, pathophysiology changes and progress of diabetes.
Despite the many challenges presented by the complex etiology of asthma, significant progress has been made in recent years to understand the environmental factors involved in disease development, with particular emphasis on the role of intestinal bacteria.
Disease etiology is unknown but progresses in the understanding of its pathogenesis have shown that MM precursor cell transformation into a malignant one occurs in a multistep process.
Currently, progress on the etiology, diagnosis and treatment of ADHD is hindered by the limited number of experimental models.
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