Exact(18)
The etiological link between tumorigenesis and the chronic inflammation is well documented for gastric cancer, which is associated with Helicobacter pylori infection and chronic gastritis, and colorectal cancer, which is frequently associated with inflammatory bowel disease (IBD) (Ferrone and Dranoff, 2010; Grivennikov et al., 2010; Zitvogel et al., 2012).
The absence of variants in 7,197 and additional control X-chromosomes and abnormal functional studies support an etiological link.
Although the etiological link between HCC and HBV and HCV is well documented, the influence of HIV infection and immune status on the development of this type of liver cancer is unclear and particularly pertinent for Africa [81].
Errant and persistent PTEN inactivation by the same molecular mechanism might favor tumor progression and provide an etiological link between 'smouldering' inflammation and certain cancers, especially colorectal cancer, where both the PTEN and the APC tumor suppressors restrict nuclear β-catenin signaling [27].
Case-control studies would be more feasible to establish an etiological link in the correlations.
Persistent PTEN inactivation may provide an etiological link between inflammation and colorectal cancer [ 15, 16].
Similar(42)
Using a genetically sensitive design, we investigated the etiology of academic performance in Science in elementary school, and its etiological links with other academic abilities and general cognitive ability (g).
Policy makers in transitional middle-income countries especially need local longitudinal data to confirm suspected etiological links between oral health and quality of life.
However, there are few attempts to use the GWAS approach to explore the shared (pleiotropic) genetic factors, which may give clues to underlying etiological links between these diseases and pinpoint potential directions and practical recommendations for future research in this field.
Contrary to this, all four language measures displayed weak etiological and phenotypic links with autistic traits, which extended across three autistic trait domains and to the extremes of the general population.
The holistic MPE approach enables us to link potential etiological factors to specific molecular pathologies, and gain novel pathogenetic insights on causality.
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