In the SAHS, the crude incidence of type 2 diabetes was ethnicity dependent, with Mexican Americans having a greater incidence of type 2 diabetes than Caucasians (7.9 vs. 3.5%, P = 0.002).
Therefore, it is possible that given the racial/ethnic variations in both TG and HDL-C levels, the association of the TG/HDL-C with IR may be ethnicity dependent.
Collectively, these data suggested the context- and ethnicity-dependent risk determination of different PPAR- γ SNPs.
In addition, as an HIV co-receptor, this gene was recently reported to interact with the ethnicity-dependent differential prevalence of HIV, especially HIV2 in African Americans [ 33].
Based on our PFRM findings in the Marin population, future studies should now explore the age- and ethnicity-dependent mechanism potentially connecting inherited aldosterone-altering CYP11B2 variants with premenopausal predisposition to PIH or preeclampsia, and postmenopausal breast cancer risk.
Interindividual variabilities in the metabolism of nicotine are due to the gender- and ethnicity-dependent differences in the activity of enzymes (CYP2A6 and UGT1A) or, to some extent, genetic polymorphisms of the CYP2A6 gene [ 15].
This contribution of genetic background to disease phenotype could find its human correlate in the different, ethnicity-dependent frequencies of longitudinally extensive transverse myelitis seen at onset attack in 53 % of Caucasian vs. 33%% of Afro-Caribbean patients in an UK cohort of NMO patients [ 16 ].
25 In countries like the USA, where the national health data are primarily collected by race, 26 many studies have included race and ethnicity as dependent variables.
The independent variable was ethnicity and the dependent variable was the height or z-score for height/age.
The second step of the model added parents' education in order to see whether differences in socioeconomic background mediated the relationship between ethnicity and the dependent variables.
The personal and social data collected included date of birth, postcode, living arrangements (i.e., living on own, living with spouse, living with others), dependents, ethnicity, education, employment status, home ownership and annual income.
