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Moreover, screening of ethnically relevant controls (French/Caucasian, 238; Vietnamese, 115; Indian subcontinent, 252) failed to identify these variants.
The availability of ethnically relevant clinical evidence is important for clinical management at the individual patient level [ 8].
A second prerequisite for genetic association studies is a catalog of the variable positions within the candidate genes, preferably ascertained in an ethnically relevant population.
Therefore, to optimize MS treatment pathways and improve patient clinical outcomes, it is important to investigate the efficacy and safety profile of fingolimod using ethnically relevant data.
The present study was aimed to provide additional data on the short-term safety and tolerability of fingolimod in more ethnically relevant MS patient population in Latin American countries.
The results of the short-term FIRST LATAM study provide ethnically relevant Latin American patient data, which are consistent with the results from the overall fingolimod clinical trial program.
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It was hoped that by doing so we would provide a geographically diverse, ethnically varied, clinically relevant and more definitive estimate of the psychological health of this patient group.
Development of ethnically focused and culturally appropriate treatment approaches is highly relevant to clinical management of the growing HIV epidemic among minorities.
Ethnically the Baduys belong to the Sundanese ethnic group.
However, while the assumption is reasonable for homogeneous cohorts, it might not be met when there are relevant covariates which confound genotypes, e.g. ancestry principal components in ethnically mixed studies.
In response to this need, we conducted a community based epidemiological study, developed by and in partnership with the clinicians serving the local population, to provide relevant prevalence estimates of mental and physical health symptoms in an ethnically and socioeconomically diverse, geographically defined, inner city community.
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