In addition, an ethnic-dependent association has been suggested between this polymorphism and pain perception [ 29].
As mentioned above, body composition is an ethnic-dependent trait and is quite different in Asians, Caucasians, and Africans.
Several authors have shown that allele frequencies of the T102C polymorphism may be ethnic-dependent [ 34, 36, 44].
Given that several authors have shown that the frequencies of TPH-1 and TPH-2 gene variants may be ethnic-dependent, we decided to perform a sub-group analysis by populations.
Our results indicated that miR-200c expression is downregulated in LYO as compared with MYO in an ethnic-dependent manner, which to some extent is influenced by hormonal exposure.
Consequently, mining of SNP frequencies from HapMap and other genomic data sets including Affymetrix 500 K and Illumina 100 K SNPs with an ethnic-dependent background across the genome is an economical, rapid, and practical strategy for developing a more comprehensive and informative panel of AIMs [ 19, 24].
Interestingly, upon screening several alleles in the National Heart ,Lung, and Blood Institute exome sequencing project database, this genetic mutation was identified in three out of 3836 alleles of African Americans screened but none in the 8222 European-American alleles [ 38], suggesting that genetic risks for this disease are likely to be ethnic-dependent.
The identification of genetic elements underlying these ethnic-dependent phenotypic variations is a strong suggestion that the mechanisms and propagation of MNDs might be population-specific, meaning that one-size-fits-all drugs and diagnosis platforms would not be effective for all patients.
The report also found that debt might be more prevalent among black degree recipients than those from other racial and ethnic groups, while dependent white and Asian degree recipients might have higher average private debt than black and Hispanic students.
But the Telegraph added: "If we were to make one criticism it is that there was not much in the speech that spoke to the great bulk of the country - the working, aspirational families who are not poor or from an ethnic minority or dependent on the state and who sometimes feel left out of the political debate".
