The animals were killed for ethical reasons when progression of the disease was evident or when considered necessary due to old age (650 days), and their brains were harvested for subsequent biochemical and histologic analysis.
Hence, it is suggested that supports should be implemented to contribute to biology teachers' progression in ethical reasoning, such as through professional training programs.
This progression will provide the greatest adherence to ethical principles and scientific feasibility.
Other disadvantages include slow progression of DR, increased maintenance costs and the ethical issues of using non-human primates as animal models.
While a phased evaluation scheme allows for efficient, ethical research planning, in reality, it is not a rigid progression in medical testing or drug development.
The re-treatment was performed due to Ethical reasons; however as there were no cases of caries progression, these teeth were considered in subsequent radiograph evaluations.
For ethical reasons, a 2-year, placebo-controlled study could not be performed, and therefore radiographic progression in adalimumab-treated patients was compared with radiographic progression in a historical control cohort of TNF antagonist-naïve patients.
For ethical reasons, animal models are utilized in the study of prion disease transmission, inheritance, route of exposure, progression, and propagation.
Clinical trials, including disease progression recovery, would be useful and informative but difficult or impossible to apply because of ethical issues.
Assessment of disease progression has also been hampered by lack of long-term follow-up of randomised controls on both ethical and practical grounds.
