The protocol of animal euthanasia was performed according to French government ethical laws decree 86/609 and approved by the local Ethics Committee (Direction départementale des services vétérinaires de Paris, service de la protection et santé animales et de la protection de l'environnement) permit number: 75 1003.
Animal care and procedures were conducted according to the guidelines approved by the French ethical committee (decree 87-848) and by the European Community (directive 86-609-EEC).
The trial was conducted in accordance with the ethical principles decreed by the Declaration of Helsinki and in compliance with International Conference on Harmonization Good Clinical Practice Guidelines.
Mice were housed and cared for in an appropriate biohazard prevention area (A3) according to European (directive 86/609/EEC) and French ethical committee (decree 87 848) guidelines.
Animal care and procedures were conducted according to the guidelines approved by the French ethical committee (decree 87 848), by the European Community (directive 86-609-EEC) and the University of Melbourne Animal Ethics Committee based on National Health and Medical Research Council guidelines.
In ethical matters, he decreed that a man's actions are judged good or bad according to their cause and intention, except those acts that are evil by nature.
The experimental research procedures met Laws 6.638/79 and 9605/98, Decree 24.645/34, the Ethical Principles of Animal Experimentation, the Principles for Research Involving Animals [ 22], and other directives governing animal research.
The experimental research project followed Laws 6.638/79 and 9605/98, Decree 24.645/34, regarding the Ethical Principles of Animal Experimentation, the Principles for Research Involving Animals [ 16], and other guidelines that regulate animal research.
All animal procedures were performed under authorizations of the "Direction des Services Vétérinaires de Paris" of the "Prefecture de Police de Paris" and strictly followed the guidelines for the ethical treatment of the animals set forth by French law (decree N° 87-848 dated 11/19/1987 and modified by the decree N° 2001-464 dated 5/29/2001).
All experimental procedures were approved by the local ethical committee (CEEA - PRBB), and met the guidelines of the local (Catalan law 5/1995 and Decrees 214/97, 32/2007) the European regulations (EU directives 86/609 and 2001 486) and the Standards for Use of Laboratory Animals A5388-01 (NIH).
