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All authors collectively designed and drafted the study protocol and sought funding and ethical approving.
CV, CM, IS, FF, AL, FB, ES and ME collectively drafted the study protocol and sought funding and ethical approving.
FL, ML, GG, AL, CL and JG collectively drafted the study protocol and sought funding and ethical approving.
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Patient relatives and control individuals were ascertained after written informed consent, within the frame of the medical ethical approved genetic study protocol.
This study is registered as a clinical trial in Australian New Zealand Clinical Trials Registry (ANZCTR), as ACTRN12613000483752, and ethical approved by Karlstad University Ethical Review Board, dnr C2013/88.
The study received formal ethical approval (approved protocol number- UI/EC/12/0160) from the Institutional Review Committee of University of Ibadan/ University College Hospital Ibadan, Nigeria (NHREC/05/01/2008a).
The ethical body approving this study was the Partners Institutional Review Board of the Partners Human Research Committee.
A full list of ethical committees approving this study can be found in Additional file 1.
Authors self-approve ethical approval and provide consent for participation.
Ethical committee approved the study protocol.
Our ethical committee approved the protocol.
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