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"estrangement of" is correct and usable in written English
It is typically used to describe a state of being disconnected or alienated from someone or something. You can use it in sentences to express the idea of a separation or rift between people or entities. Example: The long-standing feud between the two brothers had led to an estrangement of their once close relationship.
Exact(57)
Despite the estrangement of Serbs and Albanians, diplomacy is proceeding.
It also accelerated the growing estrangement of Westminster and Holyrood.
His estrangement of the audience's expectations created something new.
The Iconoclastic Controversy had aggravated the estrangement of the Byzantine Church and Empire from the West.
Mr. Magovern accused the Smileys of "creating a permanent estrangement" of Matthew from his biological family.
The estrangement of liberal Americans from patriotism is a recent turn.
These works are among the enduring expressions of the absurdity and estrangement of modern life.
Long the friendliest of archrivals in public, there have been signs of estrangement of late with disagreements over tour politics.
The deepening estrangement of Afghanistan's non-Pashtun communities presents a paradox for the Americans and their NATO partners.
This affair matters most because it makes clear the estrangement of professional politicians from their wider parties.
She switches perspectives gracefully in order to convey the anger and estrangement of each member of the McHugh family.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com