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In this context, measuring cell surface levels of MC1R is not an adequate estimation of the availability of this protein to the T cell system.
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Due to the exploratory nature of the study, we based our sample size estimation on the availability of the data and feasibility.
One of the problems associated with an estimation of the regional availability of health care is that patients frequently travel outside their residential areas to seek care, especially those residing in remote and non-urban areas.
It also encompasses theoretical, mathematical activities, such as the design and analysis of algorithms, performance studies of systems and their components by means of techniques like queueing theory, and the estimation of the reliability and availability of systems by probabilistic techniques.
Additionally, we calculated the NADH regeneration rates and the fluxes through the soluble transhydrogenase for an estimation of the reduced cofactor availability in the cells (Table 3).
One of the problems associated with the estimation of regional availability of health care is the fact that patients often travel beyond their cantonal borders to seek care, especially those living in remote and/or non-urban areas.
The key issue in traditional test parameter estimation is the availability of a "gold-standard" test, i.e. a test whose outcome can be directly interpreted as presence or absence of disease/infection.
While these catchment models are powerful in the estimation of water availability, they are not suitable for long-term average water availability simulation.
The estimation of network availability, failure rate, and other reliability-related factors is very straightforward, if somewhat tedious, given a particular topology, known component failure rates, and repair times.
There is always a trade-off between the estimation performance and the "availability" of the measurements and/or the "accuracy" of the predictions.
Standard models exist for estimation of link availability and reliability, however a detailed analysis is beyond the scope of this paper [27].
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