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Analyses used two-tailed estimation of significance.
The main focus of this work was the estimation of significance of viral RC in the clinical context.
It also provides a statistically rigorous estimation of significance.
The proposed method allows a biologically meaningful estimation of significance for metabolic network properties.
The next generation of genotyping chips should allow more accurate estimation of significance thresholds with application to a wider range of genomic variation.
Analyses used two-tailed estimation of significance, and due to multiple numbers of comparisons, p < 0.01 was considered to be statistically significance (adjustment with Bonferroni method).
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Two-tailed estimations of significance were used, and the level of significance was set at P < 0.05.
However, for other more complicated meta-analysis methods, the transformation function cannot be determined accurately leading to under- or over-estimation of significance, and ConReg-R can provide the polynomial function approximation for the unknown transformation.
Two-tailed estimations of significance were used, and the level of significance was set at p < 0.05.
In addition to modest, at best, estimations of significance, EMSA bands I and II did not distinctly resolve on autoradiographs in many variants we studied, including wildtype.
Estimation of Statistical Significance All analyses to estimate statistical significance (Wilcoxon rank-sum, Kolmogorov-Smirnov and Fisher's exact test) were carried out using the R statistical analysis package.
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