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Calculation of EARs is also contingent upon accurate HES data and ONS mid-year population estimates which are based on estimation of changes since the 2001 census.
In this study a one-dimensional (1D) floodplain sedimentation model was developed that estimates average sediment accumulation over floodplain sections and that can be used for estimation of changes in floodplain sedimentation caused by landscaping measures.
This method is based on the estimation of changes in the flexibility matrix.
RSM allows easy estimation of changes on the response surface as changes are imposed on the design parameters.
For instance, POLFLOW has been separately used for the estimation of changes in surface and groundwater resources (Jarsjö et al. 2004; Durdu 2005).
The estimation of changes between different forest fragmentation types and their associated biomass loss can provide an estimate of degradation carbon emission factors.
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Separate estimates were obtained for different methods for estimation of change, like the indirect method (difference between predictions of biomass for each of the two measurement dates) and the direct method (direct prediction of change).
The most straightforward estimation of change between 2 occasions is the combined current estimator, ( widehat{overline{Y}} ), minus the mean calculated at previous occasion, ( {widehat{overline{X}}}_I ) widehat{overline{C}}=widehat{overline{Y}}_{wIdehat{overline{X}}}_I (10).
We have applied these methods to the estimation of change-points in time series data of multiple biomarkers, including CA125 and others, using data from a nested case-control study of women diagnosed with ovarian cancer in UKCTOCS.
Once the estimates of the current mean ( widehat{overline{Y}} ) and its variance V(( widehat{overline{Y}} )) are computed, an estimation of change ( widehat{overline{C}} ) and its variance V(( widehat{overline{C}} )) can easily be obtained.
We used Eris, a protein stability prediction server [68] that employs improved Medusa force field [69] for estimation of change in free energy difference (ΔΔG) upon mutation.
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