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The area under the ROC curve was 0.86 for the estimation group and 0.81 for the validation group.
Clinically relevant variables were analyzed in a cohort of 476 consecutive untreated patients (estimation group, 351 patients; validation group, 125 patients) with chronic hepatitis C who underwent a liver biopsy.
Therefore, we have a (partial) out-of-sample analysis for the subsequent observation at the borrower level for all three calibrating groups because the calibrating group and the estimation group always differ.
Data from the estimation group (1351 patients) and the validation group (2208 patients) were retrospectively analysed.
The area under the ROC curve was 0.887 for the estimation group and 0.875 for the validation group.
The clinical background of HCC and non-malignant CLD patients in the estimation group are shown in Table 1.
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From the propensity score estimation, groups including coordinated and non-coordinated farms that share similar observable characteristics are generated, making sure that each group benefits the balancing property.
This phylogeny estimation grouped RETA with M. mitochondrii, to the exclusion of the derived rickettsial families Anaplasmataceae and Rickettsiaceae.
Phylogeny estimation grouped all of these chromosomal-encoded proteins in a clade with other alphaproteobacterial homologs, including uncharacterized phage proteins encoded in several Wolbachia genomes (supplementary fig. S8, Supplementary Material online).
The fold change estimations (group mean Ct differences) from the three methods are highly correlated (left panel of Figure 6).
For a population of 10 million inhabitants in Portugal, we calculated a conservative estimation of group 1and group 4 PH annual incidence of at least 1.5 and 1.1 patients per million, respectively.
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