Exact(1)
An E-R model may be used for estimating trial outcome at doses not included in the pivotal trials, and cases exist where such doses have been approved based on E-R. 25 Time will show if increased focus on E-R analyses will stimulate more applications of this kind, thus providing attractive opportunities in terms of cost and time reduction.
Similar(59)
The present work compares 8 different models for estimating trial-by-trial activation patterns for a range of rapid event-related designs varying by interstimulus interval and signal-to-noise ratio.
Using errors-in-variables regression weighted by trial size, and assuming minimal uncertainty (reliability coefficient 0.9) estimating trial-level systolic and diastolic blood pressure reduction, the STE for systolic blood pressure is 7.1 mmHg and the STE for diastolic blood pressure is 2.4 mmHg.
In some circumstances one might want to estimate trial by trial SNA.
Amplitude, timing and duration are estimated trial-wise for aSCR within an anticipation window.
Amplitude is estimated trial-wise for eSCR, where duration and timing (i.e. delay) are assumed to be constant across trials (and delay is estimated from a principal component analysis [PCA] of all responses each dataset).
In general, participants estimated trials from frontal wind directions to be faster than those from rear wind directions for all three wind speed conditions (for all significant post-hoc comparisons, see Appendix Table 3).
Called the "driving force" by the Daily News in changing Bloomberg's mind by estimating the trial's cost at a whopping $217 million per annum.
In estimating the trial event rate for breast cancer it was assumed that no further increase would occur.
Even though the conventional meta-analyses of non-fatal myocardial infarction, composite microvascular complications, and retinopathy indicated a statistically significant effect estimate, trial sequential analysis showed that sufficient evidence was not yet available for a conclusion to be reached.
First, the slope is obtained for the observed firing rates at trials preceding the estimated learning trial.
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