We also performed a time-course measurement of TIMP1 and TIMP2 concentration in the conditioned medium to estimate the secretion rate of these proteins for all three cell lines (Figure 6b).
Concentrations of selected cytokines within the various culture supernatants were determined by MAP in order to estimate the secretion activities of the cells (Table 2).
A Bayesian inference methodology was used to estimate the VEGF secretion rates and aflibercept degradation rate (Table 2).
Because of the observed indirect effects of continuous B-cell depletion on (auto antibody secretion derived from mature, presumably long-lived plasma cells, we intended to further illustrate this observation by estimating the survival of ACPA-IgG secretion, total IgG secretion and protective antibody secretion (that is, measles-IgG, mumps-IgG and rubella-IgG).
The most commonly used methods/models for estimating the rate of insulin secretion include the deconvolution method (S33) and combined models assuming single- S34) and double-(single- S34tmentanddouble- S35ce kinetics of both the peptidouble- S35
Human physiological period length was estimated via the secretion pattern of the hormone melatonin in two different groups of sighted subjects and one group of totally blind subjects, each using different methods.
Total glucose disposal (TGD) rate was obtained by adding rEGP2 to M. The insulinogenic index (Δinsulin0-30/Δglucose0-30) was used to estimate the early insulin secretion during the oral glucose tolerance test and the product of the TGD and the insulinogenic index as a measure of β-cell function.
The changes in the three indices estimating insulin secretion during the OGTT yielded diverging results.
Additionally, the mean cortisol level at each time point, the estimated daily secretion as given by the area under the curve and the diurnal drop in cortisol, and estimated total morning cortisol were analysed.
We did not use the oral glucose minimal model indices for estimating insulin secretion (25), which also includes the incretin response, because we did not measure C-peptide.
