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Continuity corrections were used to circumvent problems with zero counts (in one or both arms of a study) that result in difficulties with estimating ratio-based outcome measures such as the odds ratio.
This suggests that estimating ratios instead of absolute differences may be more appropriate in such data.
This suggests a conservatively estimated ratio of benefits to costs of eight.
If the estimated ratio is lower than a certain threshold, the blocking technique is immediately abandoned.
Figure 1 Diagram depicting estimated ratio of computational and experimental requirements for various methods in this review.
The estimated ratio Ka/Ks was relatively high (0.48), but significantly lower than 1 (Z = −5.56, P = 2×10−7) suggesting that this is a relatively fast evolving gene.
This estimated ratio is just above the socially accepted threshold in the Netherlands of €20000 per QALY.
The TCS scores for tobacco prices were calculated by multiplying the estimated ratio by 30 points.
For a typical whole genome resequencing project the estimated ratio is between 0.8 and 1.0 [ 21].
Thanks to Danny Wilson for R code to estimate ratio of omegas as well as valuable suggestions and assistance with software.
This represents a median estimate of 14,000 (range 9,000 21,000) hospitalizations (Table 2) and thus an estimated ratio of hospitalizations to total symptomatic cases of 0.45% (range 0.16%1.2%%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com