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GGD and DDH estimates were calculated using the GGDC 2.0 calculator (http://ggdc.dsmz.de) with default settings.
HOMA estimates were calculated using specific insulin (SI) or radioimmunoassay (RIA) calculators (version 2.2).
Pooled effect estimates were calculated using random-effects model.
Heritability estimates were calculated using variance components analysis.
These results hold whether estimates were calculated using either fine-scale traits or coarse functional groups (Table 1; Fig. 4c).
Radiation dosimetry estimates were calculated using standard OLINDA/EXM software.
Age-standardized prevalence estimates were calculated using the 2010 Singapore adult population as the standard population.
Abundance estimates were calculated using two different methods: Conventional Distance Sampling (CDS) and Density Surface Modelling (DSM).
Confidence interval estimates were calculated using the Goodman method [17, 18].
Survival function estimates were calculated using Kaplan Meier method and were compared by the log-rank test.
Confidence intervals for FPKM estimates were calculated using a Bayesian inference method [18].
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