To get a fair performance estimate and to exclude the possibility of overfitting an experiment with 50 runs and bootstrap samples was performed.
6 We were also unable to adjust our estimates of need to exclude patients who are unwilling to undergo surgery or are not suitable clinical candidates.
In order to obtain the most reliable pooled estimates, the risk to exclude potentially original studies was preferred to the risk to reuse data from the same set of patients.
Depending on the objective of the study, in a final confirmation step, the contribution of the identified candidate compound to the measured effect should be quantified or estimated in order to exclude that major contributors have been overlooked.
Disease-free survival, the time from initiation of therapy to disease progression or relapse, was also estimated in order to exclude the impact of early TRM or non-lymphoma-related death.
This conclusion is contingent on conditions of γ/ELF exposure used and the power of the study that we estimate to be sufficient to exclude an overall ELF effect of 10 15% (2SE).
However, at present, it is unrealistic to exclude those estimates [including, for example, Wang and Feng (2016)] that use the total historical production data since they hold a dominant position, and we still lack high-quality conventional oil production data.
Having said this, we acknowledge that our estimates are not sufficiently precise to exclude falls of approximately 4 percentage points in labour supply, which is within the range of 4 6 percentage points estimated in the literature.
However, our estimates were imprecise and unable to exclude a treatment benefit of 13, 33, and 69% for the outcomes of mortality, myocardial infarction, and ischemic stroke, respectively.
The model of best fit was selected for each subject by two independent statisticians blinded to treatment group based on a set of pre-defined evaluation criteria: possible data errors; outliers affecting model fit and whether to exclude them; estimated modeled baseline and fit of model in baseline region; estimate of PC90 and fit in these regions; and closeness of model fit with observed data.
