The development of other methods to estimate sufficient important change could lead to new perspectives.
A key decision is defining the change in the estimate sufficient to warrant reviewing the DAG.
To our knowledge, this is the first reported case of recurrent IPD in a pneumococcal vaccinated adult with hyposplenia and an estimated sufficient antibody response.
We used G ∗Power software, version 3.1.5 (Universität Kiel, Germany; http://www.psycho.uni-duesseldorf.de/abteilungen/aap/gpower3/download-and-register/) to perform a priori power analysis to estimate sufficient sample sizes to achieve adequate power for z-testing of two independent proportions.
Limited pharmacokinetics was carried out on 14 patients; a sample size of 10 15 patients was estimated sufficient for the purpose of determining reliably plasma concentrations in glioma patients and allowing for cross-study validation.
We used G*Power software (Germany, version 3.1.5, http://www.psycho.uni-duesseldorf.de/abteilungen/aap/gpower3/download-and-register/) to perform a priori power analysis to estimate sufficient sample sizes to achieve adequate power for z-testing of two independent proportions.
We used G*Power software (Germany, version 3.1.5, http://www.psycho.uni-duesseldorf.de/abteilungen/aap/gpower3/download-and-register/) to perform priori power analysis to estimate sufficient sample sizes to achieve adequate power for z-testing of two independent proportions.
From previous surveys, we had information about response rates in the different groups (ranging from 35% of psychiatric inpatients to 54% of next-of-kin in paediatric care), and this information was used to estimate sufficient subsample sizes.
However, in order to obtain consistent estimates with sufficient degrees of freedom, a cutoff of a minimum of 25 observations per sector and year is introduced.
In addition, high quality commercial echosounders required for this system are currently used by industry and, with proper controls on calibration and survey design, produce biomass estimates of sufficient quality.
