Sentence examples for estimates of variant from inspiring English sources

The method copes with inaccurate estimates of variant noise patterns in the image, showing its robustness in realistic cases.

Thus there are two major advantages to iterative remapping: locally, enhanced detection of variants at both high and low frequencies in areas with dense mutation rates and globally, significantly better estimates of variant frequencies.

Most of the estimates of variant frequency for these rare conditions are based on the prevalence of a particular disorder in a population, rather than the prevalence of pathogenic allelic variants for that condition.

Building on a prior study in which we deeply sequenced 31 somatic genomes of tumors, neoplasias, and controls in six patients [ 16], we here obtain much more accurate estimates of variant allele frequencies (VAFs) of phylogenetically informative single nucleotide variants (SNVs) in a much greater number of samples, with emphasis on pre-invasive neoplasias.

To provide a more accurate estimate of variant frequency in controls that is not affected by potential differences in calling strategy in the NHLBI dataset, we randomly selected 25% of the 1492 UCL-exome samples as an 'external control set' and removed variants that appeared more than twice in these 372 'external controls'.

In case of dichotomized outcomes the effect size estimates of the variant is given as the odds ratio (OR) in those carrying the variant allele compared to non-carriers.

BEAST estimates of single variant transmissions (±95% CI) overlapped with estimated-date-of-infection based on symptoms.

In particular, conventional analyses may produce extremely unstable estimates of rare variant effects on disease and be essentially uninformative.

For 19 of the genomes reported here, 150 300 somatic substitutions were independently verified by PCR and deep pyrosequencing on the 454 platform, giving accurate estimates of the variant allele fraction for these mutations.

Users have the option to use their own estimates of passenger variant frequencies or to select from a library of pre-computed passenger frequency tables for several common cancers.

Finally, all variant-to-eigentrait effects were multiplied by the singular value matrices from the original SVD to yield main effects and standard error estimates of the variants on the original phenotypes.