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Approximately 29% (70) of the 220 proteins we identified in our subcellular fraction have predicted transmembrane domains (see Table S4), consistent with estimates of representation in other organisms [18].
This is substantially lower than the optimistic estimates of representation based on CEGMA, perhaps reflecting essential functions and constitutive expression of these highly conserved genes.
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Here we present a model based on the popular Integrated Reweighting Theory model of PL but departing from its one-layer architecture by including a novel key feature: dynamic weighting of retinotopic-location-specific vs location-independent representations based on internal performance estimates of these representations.
Comparisons with gene models of closely related taxa appear to provide a more conservative estimate of gene representation in transcriptome assemblies.
An estimate of the representation of all Alu and L1 sequences was obtained by dividing the number of probes on the array by the total number of sequences in each subfamily.
We knew the number of ICU beds in our survey and based the estimate of national representation on this number; there was no national information on the number of beds in general and university hospitals separately, and therefore we could not reliably derive a specified incidence of severe sepsis by type of hospital.
This brings us to the goal of the present study: to investigate whether the performance advantage of DM translates into better initial estimates of the sparse representation of the dereverberated speech features, compared to that obtained with MDI.
Deconvolution of gene expression profiles for heterogeneous samples can be performed accurately when sufficiently accurate estimates of the proportional representation of component cell types in each sample are available and when expression profiles of the components are sufficiently different.
Deconvolution of expression profiles when estimates of the proportional representation of component cell types in each sample are not available can be performed accurately in cases, such as that of Abbas et al. [ 7], in which careful preliminary studies have been conducted to identify expression profiles of signature genes from pure samples that clearly distinguish the cell types.
In addition, temporally-resolved estimates of a low-dimensional representation of the velocity vector fields are obtained through the use of proper orthogonal decomposition and spectral linear stochastic estimation and show good agreement with independent phase-locked PIV measurements.
In addition to a simple description of the presence of known and unknown viruses in these environments there have also been some attempts to 1) understand the biological relevance of these findings and 2) estimate the representation of the overall viral biomass.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com