Sentence examples for estimates of linkage from inspiring English sources

2. Development of 44,100-SNP Affymetrix custom array: the 44,100-SNP array was designed to provide genome-wide coverage of the rice genome at ~1 SNP/10 kb, a density that was expected to support association mapping (see section on "Estimates of linkage disequilibrium below for rationale).

Development of 44,100-SNP Affymetrix custom array: the 44,100-SNP array was designed to provide genome-wide coverage of the rice genome at ~1 SNP/10 kb, a density that was expected to support association mapping (see section on "Estimates of linkage disequilibrium below for rationale).

Estimates of linkage disequilibrium were calculated using the Haploview program [31].

Inclusion of incorrect data in genetic analysis can lead to an inflation in genetic map distances [43], an increase in type I error and/or a decrease in statistical power in association studies [44], [45], or to biased estimates of linkage disequilibrium [46] and other allele-frequency related parameters [47].

Estimates of linkage distance in WILD2 are based on female (ZW) recombination, and estimates of linkage distance in MEX1 are based on recombination in both sexes.

Estimates of linkage disequilibrium were performed using the statistical package Arlequin 3.0 [ 48].

Summary statistics-based methods typically require estimates of linkage-disequilibrium (LD) between markers as input.

The LOD score is a statistical estimate of linkage; it is the ratio of the likelihood that a chromosomal region is linked to the phenotype of interest over the likelihood that it is not.

We used the fifty kb threshold because it is the most conservative estimate of linkage disequilibrium [55] and because, at higher distances, it becomes unsurprising that a locus is proximal to one of the 226 target genes.

The value 0.5 was chosen to give a conservative estimate of linkage blocks.

The estimate of linkage disequilibrium between the polymorphisms in Spanish cases and controls combined was performed using SNP_tool package.