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Also, selection bias for non-genetic covariates that can not be corrected by PCA could lead to misleading estimates of interactions [35].
And thirdly, the spread of the estimates of interactions was consistent with chance.
Estimates of interactions are incorporated in a single table to make the output easily read.
With respect to disability, all the estimates of interactions are less than one, with the interactions between CVD and diabetes, CVD and chronic pain and lung disease and chronic pain all statistically significant and around 0.5.
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By comparing the results with randomized controllers, we obtain estimates of interaction probabilities.
In this paper, interaction-weighted travel times are computed from a matrix between regularly distributed points at fine resolution, and used together with secondary data to improve estimates of interaction weighted travel time based on commonly applied methods.
Hence, if the selected model included interaction effects, the model was again fit with MCMCglmm to obtain Bayesian maximum posterior estimates and highest posterior density intervals with 95% support (HPDI95%) for parameter estimates of interaction effects [93].
Violations of this assumption can substantially distort the estimates of interaction.
The estimates of interaction must be viewed with caution for several reasons.
No interactions were statistically significant, and estimates of interaction effects tended to be around 1 or less than 1.
Furthermore, all estimates of interaction were of small magnitude, except for the combination of obesity and heavy smoking (relative excess risk 1.5, −0.7 to 3.7).
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