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The proportion of non-duplicate, non-adaptor Illumina GA reads mapping to the aurochs (21.68%) is relatively high when compared with estimates of endogenous genetic material from other palaeogenomics surveys.
(F and G ) Estimates of endogenous levels of internally tagged Cse4 (panels C and D ).
For the first time, repetitive measurements of glutamine Ra were performed in critically ill patients giving estimates of endogenous glutamine production.
The traditional hydrocortisone replacement regimen had been 20 mg in the morning and 10 mg later in the day [ 2], based on earlier estimates of endogenous cortisol production of 12 15 mg/m/day [ 3].
This also explains why the DT and TT methods provide slightly different estimates of endogenous glucose production and fractional clearance rate k01EM while fitting identical EGP-mimicking tracer concentrations.
Estimates of endogenous 8-OHgua levels in human lymphocyte DNA are between 2 and 8 for every 10 5) unaltered bases--a high frequency in view of the potential mutagenicity of this base alteration and of the presence of an effective base excision repair pathway in eukaryotic cells.
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Glutamine rate of appearance (Ra) may be used as an estimate of endogenous glutamine production.
Ra as an estimate of endogenous production is not without problems.
The estimate of endogenous acid production has been further simplified by considering only protein and K intakes.
Also, the separate estimate of endogenous brain production rate of L-DOPA (Kin) for compartment 4 and 5 resulted in similar estimated values (5.8 min-1).
An estimate of endogenous glucose production can be obtained from the measured isotopic enrichments of infusate and plasma together with glucose infusion rate (37).
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