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RSFC-based parcellation converges with parcellation information from other modalities in many locations, including task-evoked activity and probabilistic estimates of cellular architecture, providing evidence for the ability of RSFC to parcellate brain structures into functionally meaningful units.
Hepatocellular accumulation of ritonavir during the 10-min uptake study in human SCH was 5 10-fold higher than the dosing concentration, based on estimates of cellular volume reported previously.
Of course, within- and between-laboratory reproducibility estimates are still important for validation, and hazard data should be further integrated with distribution estimates of cellular concentrations on the basis of physiologically based toxicokinetic models (Blaauboer et al. 2012; Judson et al. 2011; Leist et al. 2012b).
Mathematical models in the software use these scatter signals for calculating, for each individual cell, estimates of cellular volume (V) and cellular Hb concentration (CHC); these parameters can be specifically calculated for reticulocytes, too mean cellular volume of reticulocytes (MCVr) and mean cellular Hb content of reticulocytes (MCHr).
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We used tRNA gene copy numbers as an assumed estimate of cellular tRNA abundance.
MTT reduction assay was performed as an estimate of cellular viability, as described earlier [ 21].
We use tRNA gene copy numbers as an assumed estimate of cellular tRNA abundance (see also [ 12, 25]).
This method of calcium calibration is crude and was only intended to give a rough estimate of cellular calcium concentrations for the purposes of comparison.
This general congruency indicates that the use of an MtPt4 expression threshold should lead to a reliable identification of ARB-expressed genes and a correct estimate of cellular gene transcription in AM roots in general.
The number depicted below each graph is the corrected area (in pixels) under the respective curve and thus represents a standardized comparative estimate of cellular density within each tissue section.
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