Sentence examples for estimates of absorption from inspiring English sources
Because of the limited PK data at 540 mg (n = 4), nonlinear absorption models with various mathematical permutations did not show improvements of model fitting nor reliable estimates of absorption parameters.
The size of the dose and sampling protocols were chosen based on data from the few previous estimates of absorption, kinetics and turnover that used unlabelled and radiolabelled compounds in human subjects and animals, combined with compartmental modelling.
Fluoride is readily absorbed from the gastrointestinal tract, with estimates of absorption ranging from 75to100%0% [Agency for Toxic Substances and Disease Registry (ATSDR) 2001; Ekstrand and Ehrnebo 1980].
These estimates of absorption and general intake are averages and do not apply to children exposed to a known source of lead, and they do not apply to infants who consume formula made from tap water (Gulson 1997; Hilbig et al. 2002).
The increase in fat most likely represents small amounts of unabsorbed EO at the mid- and high-dose (estimates of EO absorption in this study are >80%).
Furthermore, there have been few estimates of dermal absorption of flame retardants from vapor.
Studies with stable lead isotopes raise some uncertainty about the difference in estimates of gastrointestinal absorption between children and adults.
Accordingly, we ascertained family members of probands for more direct estimates of cholesterol absorption using the single-isotope-labeled method of Wang et al. (17).
Regression fit of the data to the model yielded estimates of the absorption rate constant (k a ), elimination rate constant (K), and an apparent volume of distribution (V/ F; F is the implicit bioavailability term).
Estimates of apparent absorption rate constant (Ka), terminal elimination rate constants (λz) and apparent volume of distribution (Vd/F) were determined for each child using the algorithms contained in the Kinetica (version 4.1.1, InnaPhase Corporation , Inc Philadelphia, Pennsylvania, USA) software package.
In combination with mathematical modeling, estimates of gut absorption can be used to explore, in silico (34), alternative insulin dosing strategies including closed-loop systems (5, 10, 11, 13, 33).
