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In addition, these estimates are compared to local burden of disease estimates for malaria and other conditions in the same health unit over the same time period.
Using the patient record data, we found that the cost estimates for malaria admissions were disaggregated by malaria complication for patients < 6 years of age (Table 1).
Although we have case-fatality estimates for malaria patients at both hospitals based on patient records, meaningful comparisons cannot be made because of the small sample size of records for LGH, which might significantly skew these outcomes.
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If we assume no under- or over- reporting of malaria [ 41], the mean DALY estimate for malaria in Serere is 271 and that for HAT 86 (Table 5).
Similar per-patient costs were estimated for malaria admissions among patients ≥ 6 years of age, by complication and by year (Supplemental Table 3A).
For Botswana, the country with the largest estimated HIV impact, 95% CI would be 14%47%% (best estimate ≈28%) for malaria incidence and 37%–188% (best estimate 114%) for malaria deaths.
Combining the ranges of estimates from these scenarios into 1 multivariate analysis, with the Monte Carlo technique and assuming triangular distributions for all parameters, overall 95% confidence intervals (CIs) on the continentwide estimates would be 0.6%7.9%% (best estimate ≈1.3%) for clinical malaria incidence, and 3.1%17.1%% (best estimate ≈4.9%) for malaria deaths.
Efficacy estimates for clinical malaria in cohort 2 are much lower in the ITT analysis, starting at dose 1 and including the vaccination period, than in the ATP analysis, starting post dose 3.
Estimates for childhood malaria prevalence are about 30 50% in Nouna town and 75% in the surrounding district, where total annual rainfall varies between 600 and 900 mm (18).
On the basis of analysis of FOMEMA data, the estimated EF for malaria is approximately 8. If malaria is assumed to be the most relevant disease to compare with the dengue situation, we would expect to see only approximately 10 12% of dengue cases being reported to the MoH.
National coverage estimates of malaria treatment for febrile children under 5 years of age range from 70% in urban Burkina Faso to less than 10% in urban and rural Zimbabwe (Figure 2).
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