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The need for population-wide estimates across multiple injury types has been identified as a gap by recent reviews [ 26, 27].
The present meta-regression analysis aims to shed light on this specific point, by increasing statistical power and enhancing the precision of estimates across multiple modest-size trials.
A range of heritabilities reflects either the variation in estimates across multiple studies or across multiple age groups within a single study.
The accuracy of the method was illustrated by the consistency of the allelic expression estimates across multiple replicates assay within the same individual sample.
Most analyses used categorical exposure variables (deciles, lowest decile as reference), to avoid any assumptions about the shape of a parametric model, taking advantage of the large sample size that permitted adequately precise estimates across multiple categories.
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Not only were these heritability estimates consistent across multiple concentrations, but they were consistent across multiple camptothecins analogues and experiments.
Averaging estimated rates across multiple branches resulted in less erroneous estimates of rate variation.
Classical techniques for identifying significant edges in the resulting graph rely on ad hoc thresholding of the edge confidence estimated from across multiple independent realisations of networks learned from the given data.
Furthermore, the results of the classification experiments show that by fusing homogeneous nearest-estimate classifier decisions across multiple channels, the classification accuracy can be improved significantly when compared with the accuracies of individual channel classifiers.
When the number of environments is large, Chen et al. (2010) used the variance of the estimated QTL effects across multiple environments as a measure of the Q×E interaction.
To date, however, the use of quantitative structure activity relationship (QSAR) models to estimate binding affinity across multiple chemical classes has shown only modest success possibly due, in part, to a focus on minimum energy chemical structures as the active molecules.
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