The unknown parameter values were estimated using an iterative method combining global (particle swarm pattern search) [ 43] and local (downhill simplex method in multi-dimensions) [ 44] optimization algorithms.
Optimal values of the physical parameters are then estimated using the Nelder-Mead simplex method [19].
Optimal values of the physical parameters are estimated using the Nelder-Mead simplex method, which is implemented to search for the optimal physical parameters to minimize the cost function.
Model parameters were estimated using laboratory-scale batch and sequenced batch experiments using the novel Latin Hypercube Sampling based Simplex (LHSS) method.
Kinetic and transport parameters are estimated by minimizing the sum-of-squares error between the model and experimental measurements using a simplex method.
Dressing development was assisted by design of experiments, using a simplex centroid design.
Composite films were manufactured using whey protein isolate (WPI), gelatin (G) and sodium alginate (SA) using a simplex centroid design.
The models were fit so as to maximize LLE for each subject individually using a simplex method.
The search for herpes simplex in CSF, using a herpes simplex polymerase chain reaction (PCR), was performed in 126 patients but was positive in only one case.
A model function was fitted to each slice using a downhill simplex algorithm.
