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The >2600 mature miRNAs from human and ∼1900 from mouse are estimated to target about half of the genes in humans and rodents (7).
There are over 1,000 miRNAs encoded within the human genome and these miRNAs are estimated to target ~60% of genes.
For instance, a single miRNA is estimated to target an average of 100 200 mRNAs [ 10] while a single mRNA transcript can be targeted by hundreds of miRNAs [ 11] and multiple miRNAs can cooperatively repress a range of targets [ 12].
A BLAST search of the obtained high-quality reads identified 14 potential microRNAs in P. ginseng, which were estimated to target 100 protein-coding genes, including transcription factors, transporters and DNA binding proteins, among others.
Due to the redundancy inherent with partial recognition, each miRNA is estimated to target at least 200 genes, to the effect that more than 60% of the human genome could be regulated by miRNA function [ 4- 6].
Based on computer-aided predictions, miRNAs are estimated to target about one third of the human genes (17), so it is not surprising that miRNAs could play a key role in human malignancy.
Similar(53)
She is one of the lastest victims of a particularly malacious piece of "ransomware" called CryptoLocker, which is estimated to have targeted nearly 1m computers over the past month alone.
The deal, to be formally announced today, is estimated to be costing Target $750,000 to $1 million in rent alone, in addition to production and maintenance expenses.
This compares with MySpace, which is owned by Rupert Murdoch's News Corporation, which is estimated to be on target to make $347m this year.
On average, each protein has been estimated to be a target for 2.5 modifications [ 62].
It is difficult to estimate distance to target object or space between robot and environment.
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