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The researchers wrote that > Most notably, the diversity in mutation rate of single nucleotide polymorphisms is dominated by the age of the father at conception of the child… After accounting for random Poisson variation, father's age is estimated to explain nearly all of the remaining variation in the de novo mutation counts.
First, Mincer earnings equations are estimated to explain the log wages of men and women.
A bivariate probit model, estimated to explain the different types of technological innovations (product and/or process), shows that firms with strategic CSR profiles are more likely to innovate in both products and processes.
Improved mental health, measured through lower levels of depression, was estimated to explain nearly 30percentt of the benefit from living around green spaces.
However, none of the newly identified loci is estimated to explain more than 1% of the heritability.
One notable exception is the apolipoprotein E locus (APOE): the ε4 allele is common, increases AD susceptibility 3-fold, and is estimated to explain at least 10% of the population-attributable risk of disease [1].
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This evaluation consists of two components, assessing the capacity of a common variance estimate to explain the observed gene sample variances and evaluating how improving this common variance estimate can aid in the detection of differentially expressed genes.
In order to assess the capacity of a common variance estimate to explain the observed gene sample variances we will use the shrinkage coefficient λ, described in the methods section, as a statistic.
Progression of joint destruction in rheumatoid arthritis (RA) is partly heritably; 45 to 58% of the variance in joint destruction is estimated to be explained by genetic factors.
Heritability estimates for AP and ADHD in children are about 70%and75%5%, respectively, and ∼75% of the covariance between the AP scale and ADHD has been estimated to be explained by genetic influences.
The need for ongoing renal support in those with AKI is estimated to be 14%, perhaps explaining the association with outcome at 6 months.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com