Sentence examples for estimated the affinity from inspiring English sources

Ultrafiltration-based affinity mass spectrometry validated the interaction between -crebanine (1) and 5-HT2C receptor, and estimated the affinity of the ligand for the receptor (Kd ~ 0.34 μmol/L).

Using solution NMR spectroscopy, Shimada et al. estimated the affinity between Gβγ and the GIRK1 cytoplasmic domain (which accounts for the full protein protein interaction surface) to be about 250 μM (Yokogawa et al., 2011).

The distribution coefficient (k) values were used to estimate the affinity of NIPs to glabridin.

A single-point Kd calculation method established earlier for binding evaluation of pure ligands or simple ligand mixtures was then employed to estimate the affinity of each ligand to the receptor (Qin et al. 2015).

The aforementioned MD-data ("randX", where X = M1, M2, L3 and P1) were used to estimate the affinity of hPS to the related sites on the protein surface.

As a consequence, it is difficult to estimate the affinity of AMPARs for scaffold elements, or the density and distribution of scaffold proteins in the PSD.

Because of the spectroscopically quiet nature of Zn II), a metallochromic indicator, zincon, was used to estimate the affinity of Zn II) for YjiA.

However, these titrations show that addition of U2A′ significantly increases the affinity of U1A for SLIV, and fitting these data to our binding model allowed us to estimate the affinity of U2A′ for U1A [ KU2A′,app = (1.4 ± 0.2) × 10 6 M].

QDAT software (ICX Nomadics) was used to analyze the sensorgrams for the kinetics of binding (ka) and dissociation (kd) and the SPR binding curves to estimate the affinity of binding (Kd).

Titration experiments led us to estimate the affinity of CF1 for the complex to be low (3.1 mM ± 1.3; Figure 3C), as expected for a small chemical fragment (168 Da).

Orthovanadate binds to the active sites of numerous enzymes including phosphatases and kinases.[ 24] To estimate the affinity of orthovanadate for PTEN ox), we performed V NMR experiments with preoxidized PTEN.