Though not a small amount, this was dwarfed by the potential economic benefit, in the form of prevented illnesses, that the FDA estimated the regulation would bring: $3 billion.
The estimated gene regulation structure based on identified module showed clearly the negative relationship between heat shock proteins and metabolic genes.
The estimated transcription regulation structure of A. fumigatus shows that the heat shock proteins are strongly negatively associated with central metabolic pathway genes such as the tricarboxylic acid cycle (TCA cycle) and carbohydrate metabolism.
Our results further demonstrate that the estimated transcriptional regulation strengths have certain advantages over the gene coexpression approaches for exploring the regulatory relationships and can provide a new insight to the regulatory relations of between transcription factors and their target genes.
This was the reasoning offered by Bank of America CEO Brian Moynihan in October, when he estimated that regulations imposed by the Dodd-Frank financial reform act would cost his company billions.
The proposed method is applied in order to estimate the regulation frequency in train operation, considering train speed, wind direction, and windbreaks.
From the network, we can estimate possible regulation between heat shock response genes.
Ribosome profiling approaches require transcriptome determination in order to specifically estimate translational regulation.
We also estimated that metabolic regulation through 3-phosphoglycerate would contribute to the changes in biomass production and fermentation productivity.
We estimated the transcriptional regulation structure of A. fumigatus under heat shock conditions using time series microarray data with very short length of time point, i.e., 6.
