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We also present the estimated multiplication factors and their 95% CI.
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Another reason might be the data quality of both target and predictor variables: The C storage in living forest trees and dead wood for example is estimated by multiplication of the volume of adequately large trees and the tree specific density [28].
The CFR was estimated by multiplication of the hospitalization ratio calculated in the first stage and the CFR among hospitalized cases in later stages.
The overall case fatality ratio was estimated by multiplication of the hospitalization ratio calculated in the first stage and the case fatality ratio among hospitalized cases estimated in the second stage.
The cost was estimated from multiplication of the resource consumption and price per unit.
The costs were estimated from multiplication of the resource consumption and unit costs.
The indirect costs as reported by the loss of productivity was correspondingly lower for the integrated programme; 8,021 € versus 9,152 €, when estimated by multiplication of the number of days and the Danish average salary (104€ per day).
Because visits were scheduled at roughly 1-month intervals, the slopes can be interpreted as the observed average change in a given measure for 1 month on treatment; the 6-month change can be estimated by multiplication.
The absolute count of CD34/CD45 cells was estimated after multiplication of their percentage to the absolute white blood cell count determined after analysis by an automatic counter (Beckman Coulter Co).
Using multivariable regression modelling for the entire time series, we estimated the multiplication factor for the overall under-reporting to be 1.51 (95% confidence interval (CI) 1.17-1.96) for the ten-week period.
The application of different methodologies to estimate QALE (multiplication only or addition only versus multiplication and addition in the base case) also had little impact on the overall findings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com