Sentence examples for estimated lead time from inspiring English sources

Our estimated lead time is based on observation in randomised trials of screening.

Assuming an estimated lead time bias of five and a half to seven years, follow-up might not have been long enough to detect differences in mortality given the low number of deaths from prostate cancer.

This 'double-counting' gives, for example, an estimated lead time of 14.1 years in men aged 55 59 years with lower grade cancer, with the model consequently only allowing death due to prostate cancer in the final 0.9 years of the 15-year observation period.

To date, only the European Group on Tumor Markers (EGTM) suggests that an increase in serum CA15-3 often predicts clinical or radiological signs of disease recurrence in BC patients, with an estimated lead time of 2 9 months [ 10- 12].

However, the estimated lead times may be too large, as they are based on all men in a cohort with localised prostate cancer irrespective of Gleason grade (Draisma et al, 2003).

Our primary aim was to estimate lead time for clinically relevant tumours and to compare this with model-based estimates.

To avoid such overestimation, it is necessary to estimate lead time explicitly or to have a very long period of observation.

Some inconsistencies were observed in the estimated lead-time TTO valuations.

By comparison, linear regression models estimated a lead time of 12.8 and 15.8 months at >5 ng ml−1 for detecting early- and late-stage cancers, respectively, whereas at >2.5 ng ml−1, the lead time was 36.2 and 28.6 months, respectively.

8 Data from the recently completed European Randomized Study of Screening for Prostate Cancer, estimated the lead time associated with PSA screening to be 10.3 years and the over diagnosis rate to be 54%.

Auvinen et al (2002) estimated mean lead time and then inferred the MST, assuming that cancers in the first round of screening are detected on average in the midpoint of the MST.