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As shown in table S2, estimated gene expression changes may differ among the different probesets that are available in the array for each gene.
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The present study was not designed to assess bias in estimating gene expression, fold-changes or sensitivity and specificity of fold-change detection.
41, 42 Previously, Shen-Orr et al have developed a deconvolution method (csSAM), which takes advantage of complete blood cell count and differential (CBC/diff) data to statistically estimate differential gene expression changes within each cell type.
In this study, we performed scatter plot analysis in order to estimate global gene expression change.
The Cox Proportional Hazards model[6] was used to estimate the effect of gene expression changes in C/N on survival from lung cancer in smokers.
It is of fundamental importance to estimate the rate of gene expression changes among and within taxa and to characterize the underlying forces shaping evolution of the mammalian transcriptome.
Recently, we developed a 'convex basis random sampling' method [ 55], which allows for a genome-scale statistical comparison of experimental gene expression changes and estimated metabolic fluxes.
To better examine whether the two assays demonstrate similar patterns of gene expression changes, we estimated the mean differential expression of TNFAIP3, OIP5, MUL1, CTSB and BCL2L10 derived from each method with the goal of replicating the patterns of differential expression.
This paper examines the responsiveness of all genes in mouse ES cells estimated using our recently published database on gene expression changes after controlled induction of 53 transcription factors (TFs) and other genes [ 9].
They demonstrated that the technique based on gene expression changes can reliably estimate the age of Ae. aegypti mosquitoes.
We used the same approach to estimate the heritability of gene expression over time; that is, the heritability patterns of gene expression changes.
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