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The probabilities of efficacy and toxicity are estimated after applying data augmentation to missing data, and the dose combination to be allocated to the next cohort is decided using these probabilities.
35 Model estimation was carried out with a Markov Chain Monte Carlo algorithm, during which latent quantities were estimated by using data augmentation.
From the central waveforms, central systolic and diastolic blood pressure, central pulse pressure, central augmented pressure, and central augmentation index were estimated.
The key finding in this study is that baseline cardiovascular autonomic neuropathy (measured by E/I ratio) strongly correlates with both arterial stiffness (measured by both augmentation index and augmentation pressure) and reduced estimated myocardial perfusion (measured by SEVR) in childhood-onset type 1 diabetes some 18 years later.
The method utilizes an observable default model of the system together with measurement data from the real system and estimates a model augmentation.
Then the "Visilog" software was used to estimate the percent augmentation of the aggregate surface as a function of time and as a function of relative humidity.
On applying deep local anesthesia beneath the nipple, the desired amount of augmentation can be estimated by using the anesthetic to temporarily "plump" the nipple.
Recent research shows that the central augmentation index cAI can be estimated by applying a transfer function to the radial pulse augmentation index (rAI) [16],[17], or can be obtained directly from the radial pulses [18] due to high correlation.
The proportional circle imageries served as visualized descriptive augmentations to the estimated sero-positivity in the herds.
Central augmentation index (cAIx) was estimated using the same system (23).
The total number of subjects is estimated by the method of data augmentation developed by Link and Barker.
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