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Since this estimate will be derived from bootstrapping our own model, it is unreliable.
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Cost-utility estimates will be derived accordingly, using QALY differences between groups as outcome measure.
The differences between the pooled estimates will be derived and combined using random effect meta-analysis fully allowing for heterogeneity, to measure the variability in bias estimates, expressed in τ.
Health state utilities to estimate QALYs will be derived from an EQ-6D measurement at baseline, as well as the follow-up assessments.
The estimates when K≥2 will be derived through the conditional ML and their properties studied in the next section.
Studies using mobile air pollution sensors are only active on a relatively small number of vehicles for which the estimated pollution levels will be derived.
In order to estimate QALYs, utility scores will be derived from the SF-6D [ 62].
In order to estimate QALYs, utility scores will be derived from the SF12, using the SF6D algorithm [ 35, 36].
Estimates of labour costs will be derived using the activity-based costing method.
Estimates of population values will be derived by standard methods for analysing a multistage cluster sample.
Although the best estimates of EEG network synchrony likely will be derived from intracranial source estimates, the prototype has computational demands greater than those required to estimate intracranial source connectivity and thus is more than adequate to establish the feasibility of a future EEG network synchrony neurofeedback system.
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