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Confidence intervals about the density estimate were obtained by repeating the kernel-fitting procedure on 10,000 bootstrap samples of the crossovers, taking the 2.5th and 97.5th percentiles at each point at which the original kernel was evaluated.

The final estimate is obtained by computing the inverse DCT of : (6).

The following maximal estimate is obtained by Li, Wan, and Zhang [28].

Finally the horizontal and vertical components of the subpixel accurate motion estimate are obtained by computing the location of the maxima of each of the above fitted quadratics.

The ITT estimate was obtained by fitting a linear regression model with adjustment for baseline variables.

A value estimate is obtained by combining weights and scores using simple or complex mathematical models.

The risk estimate was obtained by pooling cases from twelve studies.

The final error rate estimate is obtained by averaging over the cross-validation iterations.

95% confidence interval for the heritability estimate was obtained by non-parametric bootstrap, resampling family data 5000 times.

The day case estimate was obtained by analyzing 30 cases attending Massachusetts Observation Units, who received IV steroids.

A more robust estimate is obtained by using sensitivity and specificity values obtained at multiple cut-off points to draw a receiver operating characteristics (ROC) curve.