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Variables were included in the basic model one by one and were kept for further analysis only if the risk estimate was changed at least 10%.
The potential influence of each obesity-related illness was assessed in accordance with the change-in-estimate method, 28 ie, a factor was regarded as important if the crude estimate was changed by at least 10% by adjustment.
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Negative h estimates were changed to 0 and h estimates >1 were changed to 1 and were arcsine square root transformed prior to analysis.
After reaching a consensus on job components, a number of outlying estimates were changed by each expert, and two job groups were re-evaluated by all five experts.
†Final model included only vaccination as independent variable (see footnote to table 2); adjustment factors were considered important if P<0.05 or estimates were changed by 10%.
Moreover, a sensitivity analysis excluding the two diabetic subjects with insulin only therapy showed that the risk estimates were changed with <1%.
We also examined whether estimates were changed when the study population was restricted to women with a diagnosis of epilepsy during the five years before conception of the index pregnancy.
None of the risk estimates were changed by exclusion of the 22 cases and 38 controls who had developed a cancer at a site other than the stomach before enrolment in the cohort.
[Update: The acquisition price estimate has been changed as we've learned more. Initially sources said "under $5 million".].
Considering the uncertainty, 12% and 30% as low and high estimate values were changed during sensitivity analysis.
After adjustment for maternal race, parity, age, and socio-economic index, the estimate was minimally changed (0.08 [−0.29 to 0.45]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com