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The IEDI calculation gives an unrealistic worst-case estimate of intake because it assumes that 100%% of crops with established and proposed uses will contain residues at the STMR.
Such a biomarker will then allow us a much more accurate estimate of intake.
Thus, incorporation of the cord:maternal ratio and its variability into the estimate of intake dose could result in a significant change in the value of the RfD.
In some cases, chemical measurements in exposure media (e.g., drinking water, air, house dust) may provide a reliable estimate of intake.
The association of vegetable consumption with the risk of lung cancer might have been attenuated because of error in the estimate of intake.
Advocates suggest that this adjustment provides a better estimate of intake and a tighter correlation with toxicant levels in other biofluids (Hill et al. 1995; Shealy et al. 1997; To-Figueras et al. 1997).
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Two 24-h estimates of intake were measured for each week of the study from June to August in each year.
It is important to note that the current pilot study measured the amount offered rather than the amount the infants consumed, so this will be an over-estimate of intake.
This results in lower average estimates of intake of phytonutrients using these data.
No estimates of intake or uptake for the THEP were found in the literature.
Accurate estimates of intake in populations are essential to explore these relationships.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com