Your English writing platform
Discover LudwigExact(32)
In order to decide whether a new treatment should be used in patients, a robust estimate of efficacy and toxicity is no longer sufficient.
In the first year of follow-up, largely due to cultural practices to visit traditional healers as the first point of care, the point estimate of efficacy was unreliable: the per protocol vaccine efficacy against severe RVGE was 1%95%5% confidence interval [CI]: −431.7, 81.6); the intention-to-treat vaccine efficacy was 42.9% (95% CI: −125.7, 87.7).
However, the estimate of efficacy would be 43% using objective fever, but 35% using objective fever plus subjective fever.
Allowing for potential dropout, we therefore planned to recruit at least 60 households in the control arm, and a further 25 30 households to each of the face mask and hand hygiene arms to evaluate the feasibility of the interventions and allow a preliminary albeit imprecise estimate of efficacy.
Estimates of circumcision efficacy (50 60%) were based upon results from three randomized trials [19], [20], [21] and estimates of PREP efficacy (50%) was based upon modeling studies [26], [38], with adjustments made for potential non-adherence and comparability, resulting in using a 50% estimate of efficacy for each intervention.
In five of these studies clinically significant efficacy was demonstrated against circulating H1N1 strains matched to the vaccine (ranging from 81% to 100%) while in the sixth study A/H1N1 strains did not circulate in the community which precluded an estimate of efficacy.
Similar(28)
Estimates of efficacy of drugs from clinical trials may differ from estimates in observational studies.
Oral rotavirus vaccines have yielded different point estimates of efficacy when tested in different populations.
The aim of this study was to obtain estimates of efficacy in reducing the first three of these behaviors.
Composite point estimates of efficacy (episodes of incontinence per 24-hour period, frequency, and voided volume) and safety (dry mouth, withdrawal, and dose modification) were calculated.
Techniques borrowed from clinical trials have recently allowed the impact of publication and study-quality biases on published estimates of efficacy in animal experiments to be described.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com