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Secondly, each estimate of complexity is greater than the number of genes encoded by each virus (11 and 5 for ΦX174 and VSV, respectively).
The presence of multiple functional domains within a single protein is consistent with an estimate of complexity that is greater than the number of encoded proteins.
In addition, CCEmin should be preferred to approximate and sample entropies: indeed, approximate entropy provides a biased estimate of complexity [9] and to sample entropy necessitates an arbitrary selection of the pattern length L. Older subjects revealed significant changes of time domain parameters, i.e. an increase of heart rate and a decrease of total variance compared to young subjects.
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30, 47 Note, however, that these estimates of complexity are obtained under the strong assumption that these mutations are fully pleiotropic.
Initial estimates of complexity have been based on the number of nucleotides, genes or cell types in a genome, but such bottom up estimates often fail to have useful properties [ 4, 5].
Thus, if the MPSS signature number provides a "rough first estimate of the complexity of gene expression" [ 30], Alexandrium exhibits significant transcriptional complexity, on par with multicellular eukaryotes.
Although we have only two estimates, we can briefly consider them from a comparative standpoint: although the genome size of ΦX174 is half of VSV, our estimate of phenotypic complexity quantifies ΦX174 as being approximately four-fold more complex.
Slope = the value of alpha in 1/f α; Whittle = a fractional estimate of vector complexity.
The estimate of spatiotemporal complexity is employed to modulate the propagation of the IVA in the error propagation model.
In the next section, CPU time is used as a rough estimate of computational complexity of the algorithms.
This measure is chosen since it provides a reasonable estimate of the complexity, while being analytically tractable.
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