But when a Brazilian friend in London told me that the hottest place in the country - and the new Punta del Este of South America - was an island city in the south called Florianópolis, I almost laughed.
Southern Emilia, the Romagna, the Marche, and Umbria were given up to numerous signori acting as "papal vicars," among whom the most celebrated were the Este of Ferrara and the Montefeltro of Urbino.
With Cropduster, whose music has been called "energetic, disillusioned country punk," Mr. Estes, of West Orange, has traveled to North Carolina, Pennsylvania, Upstate New York, Manhattan and throughout New Jersey.
The new technique has "very little noise," says immunologist Jake Estes of the Frederick National Laboratory of the National Cancer Institute (a sister of NIAID) in Frederick, Maryland, who used it to produce highly detailed images of the AIDS virus in various monkey tissues (above) that he presented at the conference.
And at this point, no one can accuse Estes of anything. .
The cyclone attained peak winds of 150 mph (240 km/h) as it struck Cayo Guano del Este off the coast of Cienfuegos.
Take the case of Cosmè Tura (1433-95), was was the star performer at the cosmopolitan court of the ruling Este family of Ferrara, Italy, in his day.
Titian's portrait of Isabella d' Este, marchioness of Mantua, which hangs in Vienna's Kunsthistorisches Museum, shows her as a twentysomething beauty, soft skin unblemished by wrinkles, in the bloom of youth.
Praise from the humanist Bartolomeo Fazio (Facio) and the eminent theologian Nicholas of Cusa is recorded; Rogier also received commissions from the powerful Este family of Ferrara and the Medici of Florence.
And Hozier, looking to bring some edge to his middle-of-the-road profile, brought out Este Haim (of L.A.'s Coachella-approved sister trio Haim) for a cameo that made him seem only more square.
Centuries ago, the Este family of Ferrara produced sopraffino.
